This location is soon invaded by alien-like creatures who start attacking inmates and other personnel. Leon Ferris was the first intentionally made "alpha" he is the only successful result of the Callisto Protocol.The premise for The Callisto Protocol revolves around the seemingly mundane life of Jacob, an inmate brought to Black Iron Prison. Their body was used for later modifications of the Biophage Pathogen to increase more "alphas." Subject Zero was the first technical "alpha" reaping the benefits until their later demise by security forces. Therefore, it is safe to assume "Alphas" are meant to be a perfectly evolved variant of humans that are considered "alpha" compared to non-infected human. "Alphas" presumably have gotten the name due to the Commonality's idealization and obsession with natural selection and evolving humanity to perfection. However, higher levels of aggression and hostility still seem apparent. "Alphas" refer to victims of the disease that have managed to reap the benefits of rapid evolution while keeping the benefits of cognitive functions and empathy. Victims of the disease will inevitably succumb to it unless the disease is delayed via an biophage inhibitor, or cured with the help of synthesized antibodies. Loss of cognitive functions and empathy.The body was secured and transported back to the Black Iron labs for use in the original research program. An outbreak occurred however, and Subject Zero was killed by security. However, one colonist deemed Subject Zero was able to harness the benefits of greater strength, endurance, and longevity while suffering no costs to his intellect or humanity. The larvae were then transported to Black Irons' central labs of Europa.Ĭolonists were experimented on during this time, revealing the pathogens evolution accelerating nature that mutated colonists into mindless brutes. The carcass contained thousands of larvae, which were eventually revealed to be the spreading vector for the pathogen. The alien was quickly killed by security forces and later had its carcass inspected. It wasn't until the miners broke through Callisto's subterranean ocean, that an unknown gargantuan alien life-form was released.
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